Infant colic (also called excessive crying syndrome) consists of prolonged, intense, and inconsolable crying or fussiness presented by otherwise healthy infants up to 5 months of life. Although benign and self-resolved condition, colic strongly impacts the quality of life of the family by triggering parental anxiety and increasing the risk of maternal depression, shaken baby syndrome and premature breastfeeding cessation (Source: Sung, 2018).*

The microbiome is an ecosystem of bacteria living in and on your body. The 100 trillion bacteria that make up the gut microbiome are essential to human health and immunity.*

Functional gastrointestinal disorders (“FGID”) have been described as gut-brain axis disorders caused by complex interactions between gut physiology and physiological factors that ultimately alter intestinal motility, sensitivity and barrier function. The gut microbiome has emerged as a central player in the gut-brain axis and thus in the FGIDs etiology. The gut of colicky babies has reduced diversity and lower numbers of Bifidobacteria and Lactobacillus (Sources: de Weerth et al., 2013; Savino et al., 2017; Rhoads et al., 2018; Drossman, 2016)*

Infants commonly suffer from gastrointestinal symptoms that do not have an explanation and are thus diagnosed as having a functional gastrointestinal disorder (“FGID”). One in two infants develop FGIDs during the first 6 months of life and up to 75% of these children suffer two or more at the same time. Infant colic and functional constipation are among the most prevalent pediatric FGIDs, with an aggregated prevalence of 35% in infants younger than 12 months (Source: Vandenplas et al., 2015).*

The foundation for lifelong health is laid in the first 1,000 days of life–conception to year two. The development of the human microbiome during this period determines digestive, immune, and neurological health. Nouri Baby Formula Fortifier contains two probiotic strains and essential HMOs to reduce infant gut disorders, colic, and constipation.*

Human Milk Oligosaccharides (HMOs) are a collection of carbohydrate structures and the third most abundant solid component in human milk after lipids and lactose. Research shows that HMOs may optimize microbiome development in infants by nourishing good bacteria such as bifidobacteria – one of the most abundant microbes present in the intestine of a full-term, breast-fed, healthy newborn.] A healthy gut microbiota could in turn help to protect against harmful microbes and support healthy immune system development.*

Nouri Formula Fortifer includes a combination of two clinically studied probiotic strains, Pediococcus pentosaceus KABP™-041 and Bifidobacterium longum KABP™-042, for promoting infant gut health and decreasing crying time in colicky babies. These strains were isolated via a screening process specifically designed to identify strains that have a beneficial effect on infant intestinal health while also showing the ability to adhere to the gut and to have anti-inflammatory properties (Santas et al. 2015).*

HMOs are prebiotics, which are types of dietary fiber that the human body cannot digest, serving as ‘food’ for probiotics. That makes them synergistic with probiotic strains, and together these two ingredients may help to support a well-balanced microbiota and support the development of a normal immune function.

Nouri Formula Fortifer begins working immediately. Clinical studies have shown a reduction in infant colic, gut disorders, constipation, and parental anxiety within 14 days (Source: https://www.frontiersin.org/articles/10.3389/fmicb.2021.741391/full)*

Nouri Formula Fortifer can be given to your baby at any time of the day. For most effective results, administer the product at the same time daily.*

Yes, Nouri Formula Fortifer can be added into any FDA-approved infant formula. Please consult your Pediatrician.*

Yes, Nouri Formula Fortifer can be administered to breastfed babies as well.*

Studies show that the gut microbiome establishes primarily during the first two and a half years of life. The gut microbiome development during this time lays a foundation for the bi-directional communication that happens along the gut-brain axis (the pathway between your brain and your gut where chemicals such as neurotransmitters and hormones send messages back and forth). A healthy gut microbiome supports the 1,000,000+  new brain connections formed per second during these crucial first two years.