Make the highest quality, most accessible targeted gut microbiome solutions to support the body’s foundational systems.
How your gut impacts your hormones.
The estrobolome is the collection of gut bacteria that metabolize and regulate estrogen — deciding how much is reabsorbed versus eliminated. It lives in the epithelial cells lining your gut, shown here under magnification.
Estrobolome 101
Tap to explore · Estrobolome 101 →Your gut is the switch that keeps estrogen in circulation — or clears it out.
Once the liver finishes with used estrogen, it’s routed straight to the gut to leave the body.
Its bacteria make an enzyme that can reactivate estrogen and send it back into circulation — or let it go.
A balanced estrobolome clears estrogen on schedule. An imbalanced one recirculates the excess — and that’s when symptoms start.
Twice the live bacteria. One small capsule.
Our capsule-in-capsule technology shields delicate strains from stomach acid and releases them deeper in the gut — so 2× the live bacteria survive delivery compared to a standard capsule.
Three formulas to support the female microbiome.
BEST SELLERHormone Balance ES1
The hero. Clinically studied strains support hormone balance, skin, digestion, and the estrobolome at its root.
Vaginal Balance VG1
With cranberry. Clinically studied support for urinary tract health, healthy vaginal pH, and the microbiome.
Menopause Probiotic ES2
With resveratrol. Support for hot flashes, night sweats, and estrogen metabolism through the transition.
Built by women and for women like you — who want real science to solve real problems.
Find your formula in 60 seconds.
Answer a few questions about your cycle, stage, and symptoms — we’ll match you to the right gut-hormone support.