Hormone Balance Probiotic ES1
Probiotic Capsules + Plant-Based Omega Oil
Daily probiotic + plant-based omega oil formulated to support the estrobolome, the gut bacteria that metabolize estrogen.*
Save 15% on your first orderThe Daily Nouri Hormone Balance Probiotic ES1 combines clinically studied probiotic strains to nourish your estrobolome — the community of gut bacteria that governs how your body metabolizes estrogen. By supporting a healthy estrobolome, this formula works along the gut-hormone axis to:
- Support healthy estrogen metabolism & hormone balance*
- Promote weight management*
- Improve skin health*
- Support your digestion & immunity*
One capsule once daily, any time of day, with or without food. Safe for daily long-term use. Most women notice changes within 4 to 12 weeks.
Works better together
Add a second formula to your monthly delivery and save on both. Same one-capsule routine, skip or cancel anytime.
The gut microbiome doesn't just affect digestion. It regulates estrogen.
The estrobolome is the collection of gut bacteria that metabolize and regulate estrogen. It's the control point for how much estrogen is reabsorbed versus eliminated. Hormone Balance supports it at the root.
The body produces estrogen, it does its work, then heads to the gut to be cleared.
Estrobolome bacteria express β-glucuronidase, deciding what gets reabsorbed back into circulation versus eliminated.
Hormone Balance supports the microbes that keep estrogen recycling in a healthy range.
This is where the estrobolome lives.
Sectioned and stained, the intestinal mucosa reveals the crypts and villi that house your gut microbiota. Here, along the lower-GI epithelial lining, estrobolome bacteria express β-glucuronidase, the enzyme that decides how much estrogen is reabsorbed versus eliminated.
One capsule, support across your whole system.
Supports the estrobolome to metabolize and clear estrogen.
Helps smooth the hormonal ups and downs across your monthly cycle.
A balanced gut shows up on your skin: calmer, clearer, more even.
Nurtures a diverse, resilient microbiome for everyday digestive comfort.
Benefits that build, week by week.
The estrobolome responds to consistency. Here's what daily use supports across your first 90 days and beyond.
Clinically studied strains, built for the gut-hormone connection.
A targeted blend of clinically studied probiotic strains, chosen for the gut-hormone connection, delivered in one capsule-in-capsule dose a day.
A cornerstone estrobolome strain: it helps keep β-glucuronidase activity in a healthy range, so estrogen is metabolized and cleared rather than over-recirculated through the gut. Also studied for metabolic and weight support.
Works across the estrobolome to crowd out less favorable bacteria and build a diverse, resilient gut community, the foundation that healthy estrogen metabolism depends on. Human-studied alongside IMC-502®.
Paired with IMC-501® to reinforce the gut lining where the estrobolome lives, supporting a strong intestinal barrier and calm, comfortable digestion, keeping the niche favorable for estrogen-regulating microbes.
Supports estrogen metabolism through the estrobolome while reinforcing the gut–immune interface and a balanced vaginal microbiome, part of the whole female-microbiome picture.
Supports estrogen metabolism by keeping the gut environment stable and favorable for estrobolome activity. A robust, acid-tolerant strain that also eases bloating and maintains regularity.
Supports estrogen metabolism by nourishing gut-lining diversity and short-chain fatty acid production, one of the most-studied and hardiest probiotic species.
Studied along the gut–skin axis: it complements estrogen metabolism support and the clearer, more even skin that comes with a balanced estrobolome.
Not a probiotic. The plant-based omega oil that forms the protective outer capsule. Rich in stearidonic acid (SDA), a highly convertible omega-3 that supports whole-body inflammatory balance while shielding the live cultures on their way to the gut.
A capsule, inside a capsule.
Most probiotics lose potency before they ever reach your gut. Our capsule-in-capsule design seals the live cultures inside a protective second shell, so they survive the journey and release where they actually work.
The protective outer shell shields delicate strains from harsh stomach acid.
Delayed release delivers cultures to the lower gut, where the estrobolome lives.
More strains arrive alive and active, a key reason it's twice as effective.
What the experts say.
“As an Integrative Reproductive Endocrinologist, I see the profound impact hormones have on people's lives every day. I am so excited there is now a probiotic that focuses on the foundational role the gut microbiome has on hormone regulation and its downstream effects: metabolism, skin, mood, and fertility.”
“So exciting to have an everyday probiotic that actually supports women's health. The gut has endocrine inputs and outputs that regulate so much, from menstrual cycles and weight to immune function and mood. Women deserve a high-quality probiotic that promotes balance by acting at the intersection of the gut-brain axis.”
“I'm thrilled to be part of Daily Nouri's launch of our new hormone balance probiotic! By emphasizing the importance of nutrition and the role of gut health in hormone regulation, Daily Nouri empowers women to feel their best every day.”
One small capsule. A whole system in balance.
The ritual women keep.
Three months in, my cycle feels more predictable than it has in years, and I actually look forward to taking it.
It's one small capsule a day: easy to remember, easy on my stomach, and I genuinely feel the difference.
I've tried a dozen probiotics. This is the first one built around women's hormones, and it shows.
Good questions, straight answers.
01What exactly is the estrobolome?
02How is this different from a regular probiotic?
03When will I notice a difference?
04Is it safe to take long-term, including through perimenopause?
05How do I take it?
06How long does one bottle last?
Give your estrobolome a daily ally.
Subscribe & save 10%. 30 capsules, one a day, free shipping, cancel anytime.
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