Shared by 1,400+ cliniciansThird-party testedVegan & allergen-freeMade in the USAWomen-owned
Hormone Balance Probiotic ES1 ★★★★★4.5 · 1,400+ reviews

Take control of your digestion all cycle long.

★★★★★"I noticed a marked difference by week two." · Kimberly C., Verified Purchase
$80.28 $94.44
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Recommended 90-day start. 3 bottles ship together · Free shipping · Cancel anytime

Your digestion changes across the month because your hormones do. Regular one week, sluggish and bloated the next. Hormone Balance ES1 is the daily probiotic built for the estrobolome, the gut bacteria that regulate estrogen, so you can take control of the gut–hormone connection instead of waiting out each phase. Your gut supports your hormones. Your probiotic should, too.

  • 7 clinically studied strains, 12 billion CFU, chosen for the gut–hormone axis
  • Plus 265 mg Ahiflower® Omega 3·6·9 for a calm gut lining, no fish oil
  • One small capsule a day. No hormones, no laxatives, no diuretics, no charcoal

Free shipping on subscriptions · Cancel anytime · Shared by 1,400+ clinicians including OB/GYNs

Daily Nouri Hormone Balance Probiotic bottle with capsules on a wooden board
Shared by 1,400+ cliniciansThird-party testedVegan & allergen-freeMade in the USAWomen-owned
Solving The Problem You're Experiencing

Digestion that runs on your cycle, not on what you ate.

You have already tried the obvious things. More fiber, less dairy, more water, fewer late meals. It helps for a while, then a new phase of your cycle arrives and your gut behaves differently again. If the pattern below looks familiar, this page is for you.

Bloating that builds in the second half of your cycle and fits your waistband differently by week three

Looser stools or cramping in the first days of your period

Constipation or slower digestion in the days before you bleed

Gas, heaviness and a tight feeling after meals that normally sit fine

Sugar and salt cravings in the same window your digestion slows

Breast tenderness, mood swings and PMS that arrive with it

A few good days mid-cycle, then the pattern repeats

It has become less predictable in your late thirties or forties

In a study of healthy women, roughly three in four reported gastrointestinal symptoms before or during their period, including bloating, abdominal pain and changes in stool.4 It is not in your head, and it is not your dinner.

The Simple Explanation

Your hormones shift across the month. Your digestion shifts with them.

1

Your gut slows down

After ovulation, progesterone rises. Progesterone relaxes smooth muscle, including the muscle that moves food through your gut, so transit slows and gas has more time to build.5 That is the sluggish, heavy, bloated second half of your cycle.

2

Then everything speeds up

When progesterone falls and your period begins, prostaglandins rise and the gut contracts more, which is why the first days of your period often bring looser stools and cramping. Estrogen shifts also change how your body holds fluid in the days before.6

3

Your gut bacteria set the baseline

A group of gut bacteria called the estrobolome decides how much used estrogen is cleared versus reabsorbed.1,2 When it is out of balance, the monthly swing is bigger, and so is every digestive change that rides on it.3

This is why food rules only get you so far. A new diet does not change your progesterone, and a laxative does not change your estrobolome. Taking control of your digestion means supporting the bacteria that sit between your gut and your hormones.

The Gut–Hormone Connection

Your gut supports your hormones. Your probiotic should, too.

Most probiotics were designed for digestion alone. That is a fine job, but it is not this job. Cycle-driven digestion sits at the point where your gut and your hormones meet, so the probiotic that helps you take control of it has to be built for both.

Why Hormone Balance

Seven strains chosen for the gut–hormone axis. Nothing else in it.

Hormone Balance ES1 is the daily probiotic built around the estrobolome, the gut bacteria that decide how much used estrogen is cleared and how much is reabsorbed. When that system is in balance, the monthly estrogen swing is smaller, transit stays regular through the luteal phase, and the gut lining stays calm. That is the gut–hormone connection, and supporting it every day is how you take control of your digestion through every phase.

12 BILLION CFU

The 7-strain probiotic complex

Seven clinically studied strains selected for women's gut–hormone health, not a generic digestive blend repackaged for women. Lactobacillus species in particular have been studied for their effect on bloating, abdominal discomfort and regularity in controlled trials.7

L. gasseri KABP™-064 L. rhamnosus IMC-501® L. rhamnosus SP1 L. paracasei IMC-502® L. brevis KABP™-052 P. acidilactici KABP™-021 L. plantarum KABP™-051
265 MG

Ahiflower® Omega 3·6·9

A plant-based seed oil rich in SDA, GLA and ALA, included to support a healthy inflammatory response in the gut lining. An irritated gut wall is a reactive gut wall, and a calm one handles the monthly hormonal swing with less drama.

No fish, no fillers, no aftertaste. Citrus-scented capsules, one a day, with or without food.

ZeroLaxatives
ZeroDiuretics
ZeroSynthetic hormones
ZeroTop-9 allergens

Formulated for every life stage: cycling years, perimenopause and beyond. Cycle-driven digestion often becomes less predictable in the late thirties and forties as hormones fluctuate more, which is exactly when the estrobolome's job matters most.

Watch

A closer look at Hormone Balance ES1.

Verified Reviews

What women say about their digestion.

4.5
★★★★★
Based on 1,400+ verified reviews
★★★★★

Game changer for my Bloating & PMS Symptoms

"I've struggled for years with constant bloating and horrible PMS symptoms—mood swings, discomfort, and feeling completely off hormonally. I decided to give this a try, and I'm so glad I did.

Since taking this probiotic, I've noticed a huge improvement in my bloating, my mood is much more balanced, and overall my hormones feel more regulated. My PMS symptoms are significantly more manageable, which honestly feels life-changing.

I take it first thing in the morning on an empty stomach, before I drink my morning tea, and it's been very gentle and easy to stick to. I'm already on my 3rd bottle, and that alone says a lot.

This is now a non-negotiable part of my daily routine. I highly recommend!"

LaCretia Ward · Verified Purchase · December 18, 2025 · 8 people found this helpful
★★★★★

Great supplement

"I waited until I finished a bottle to write my review. I am very happy with this supplement. Pros: Way less bloating than when I started. I noticed a marked difference by week 2."

Kimberly Collins · Verified Purchase · April 25, 2026
★★★★★

The best so far

"It works for me it ease my bloating it curves my cravings I go out regularly my period comes on time its value for ur money"

Sasha · Verified Purchase · July 17, 2026 · 8 people found this helpful
Why Consistency Matters

Digestion responds first. Give the cycle time to follow.

A probiotic works by establishing itself in your gut, and that is dose- and time-dependent. Cycle-driven digestion adds a second clock on top: your hormones. You cannot judge a cycle-driven pattern in less than a cycle. Here is the arc most women describe.

Weeks 1–2

The gut settles first

Digestion is the fastest-responding piece. Less gas, more regular days, and a flatter evening. This is the window Kimberly describes, and it is the most common first change we hear about.

Weeks 3–6

The swings get smaller

One to two cycles in is where the phase-to-phase changes soften: less slowdown before your period, a calmer gut when it starts, and PMS that is easier to live with. The first full cycle is the real test.

Weeks 7–12

The compounding window

By the third cycle the pattern is usually clear. Digestion that used to change every week feels steadier and more predictable, and you feel in control of your gut across the whole month.

Consistency beats intensity. One capsule, every day, for three cycles. Missing a day will not undo your progress, but starting and stopping means you never get past the first cycle, which is the one that tells you nothing. That is why the recommended starting point is 90 days.

Proof

1,400+ clinicians, including OB/GYNs, share it with patients.

"As an Integrative Reproductive Endocrinologist, I see the profound impact hormones have on people's lives every day. I am so excited there is now a probiotic that focuses on the foundational role the gut microbiome has on hormone regulation."

Dr. Lauren Rubal
Reproductive Endocrinologist

"So exciting to have an everyday probiotic that actually supports women's health. The gut has endocrine inputs and outputs that regulate so much, from menstrual cycles and weight to immune function and mood."

Dr. Francie Broghammer
Psychiatrist
Your Starting Point

Start with 90 days. Three cycles is how long it takes to judge it.

One capsule a day, 12 billion CFU, 265 mg Ahiflower®. Three bottles ship together so you never run out mid-cycle, and 15% off your first order applies automatically, no code to remember.

Try it without the risk

If Hormone Balance isn't right for you, contact us at hello@dailynouri.com within 30 days of delivery and we'll send a prepaid return label and refund you in full. Subscriptions have no minimum. Change your delivery frequency, skip a month, or cancel in two clicks from your account.

Before You Buy

Questions women ask us about digestion

How do my hormones affect my digestion?+

Progesterone rises after ovulation and slows gut transit, which is why the second half of your cycle can feel sluggish and bloated. When your period starts, progesterone drops and prostaglandins rise, which can speed things up. Estrogen shifts affect fluid balance too. If your digestion tracks the month rather than the meal, it is hormonal, and food rules alone will not fix it.

How quickly will my digestion improve?+

Digestive changes often come first, within the first two weeks, which is the window Kimberly describes at the top of this page. The cycle-driven pattern usually takes one to two full cycles to shift, because you have to go through each phase to see the difference. Judge it at three cycles.

Will it make me gassy at first?+

Some women notice a few days of adjustment as the strains establish themselves, usually mild and gone within the first week. Most notice nothing but a gentler gut. Taking it at the same time each day, with or without food, keeps it smooth. If you are sensitive, start with it at breakfast.

Is this a diuretic or a laxative?+

Neither. There are no diuretics, laxatives, fibre bulking agents, charcoal or enzymes in it. Those move water or stool for a day. Hormone Balance works on the bacteria that sit between your gut and your hormones, which is where cycle-driven digestive changes come from.

Does it help with constipation before my period?+

Slower transit in the luteal phase is progesterone doing its job, and a healthier gut microbiome handles that slowdown better. Many women tell us regularity is one of the first things to improve, and it is a common theme in reviews. It is not a laxative, so it will not force anything.

I'm in perimenopause and my digestion has changed. Is this for me?+

Yes. As cycles become irregular in the late thirties and forties, the estrogen swing gets bigger and less predictable, and digestive changes often show up or worsen. The estrobolome's role in clearing estrogen matters more in that window, not less. Perimenopause is one of the most common reasons women start.

How is this different from the probiotic I already take?+

Most probiotics are built for digestion, with strains chosen for gut comfort. Hormone Balance ES1 uses seven strains selected for the gut–hormone axis and pairs them with Ahiflower® Omega 3·6·9 for the gut lining. If your digestion runs on your cycle, you need a probiotic built for both sides of that.

Do I need to refrigerate it?+

No. Store it at room temperature, out of direct sunlight. Take one capsule daily with water, with or without food, whatever makes it easiest to remember.

Is it safe with my medication, or if I'm pregnant?+

It's hormone-free, vegan, third-party tested, and free from nine major allergens. That said, if you're pregnant, breastfeeding, or taking medication, talk to your healthcare provider before starting, as you should with any new supplement.

What if it doesn't work for me?+

Email hello@dailynouri.com within 30 days of delivery and we'll arrange a return and full refund. We'd rather you tell us it didn't work than quietly give up on it.

Hormone Balance Probiotic ES1

Take control of your digestion.
One capsule a day, all cycle long.

Seven clinically studied strains built for the estrobolome. 12 billion CFU. Plant-based Ahiflower® Omega 3·6·9. No laxatives, no diuretics, no hormones.

4.5★ from 1,400+ reviews Shared by 1,400+ clinicians Third-party tested 30-day returns

$80.28 today, was $94.44 · Save $14.16 · Free shipping · Cancel anytime

References

  1. Plottel CS, Blaser MJ. Microbiome and Malignancy. Cell Host & Microbe. 2011;10(4):324–335.
  2. Ervin SM, Li H, Lim L, et al. Gut microbial β-glucuronidases reactivate estrogens as components of the estrobolome. Journal of Biological Chemistry. 2019;294(49):18586–18599.
  3. Baker JM, Al-Nakkash L, Herbst-Kralovetz MM. Estrogen-gut microbiome axis: Physiological and clinical implications. Maturitas. 2017;103:45–53.
  4. Bernstein MT, Graff LA, Avery L, et al. Gastrointestinal symptoms before and during menses in healthy women. BMC Women's Health. 2014;14:14.
  5. Wald A, Van Thiel DH, Hoechstetter L, et al. Gastrointestinal transit: the effect of the menstrual cycle. Gastroenterology. 1981;80(6):1497–1500.
  6. Stachenfeld NS. Sex hormone effects on body fluid regulation. Exercise and Sport Sciences Reviews. 2008;36(3):152–159.
  7. Ringel-Kulka T, Palsson OS, Maier D, et al. Probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 versus placebo for the symptoms of bloating in patients with functional bowel disorders. Journal of Clinical Gastroenterology. 2011;45(6):518–525.

Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Cited research describes studies of mechanisms and of individual probiotic strains, and is not a study of this finished product; probiotic effects are strain-specific. Individual results vary. Reviews reflect the experiences of individual customers and are not a guarantee of outcome. Always consult a qualified healthcare provider before starting a new supplement, especially if you are pregnant, breastfeeding, taking medication, or managing a medical condition.